A new triterpenoid from Teucrium viscidum.

نویسندگان

  • Xincai Hao
  • Jinwen Zhang
  • Guangxin Xia
  • Yongbo Xue
  • Zengwei Luo
  • Yanyan Si
  • Guangmin Yao
  • Yonghui Zhang
چکیده

A new ursane-type triterpenoid, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyloxy-12-en-28-oic-acid (1), together with three known triterpenoids, 3β-hydroxy-urs-30-p-E-hydroxycinnamoyloxy-12-en-28-oic-acid (2), 2α,3β,19α-trihydroxy-urs-12-en-28-oic-acid (3), and ursolic acid (4), four known lignans, pinoresinol (5), 9α-hydroxypinoresinol (6), (+)-medioresinol (7), and (+)-kobusin (8), and two steroids, β-sitosterol (9), and daucosterol (10), were isolated from the whole parts of Teucrium viscidum. Their structures were established by a combination of spectroscopic data analysis, besides comparison with literature data. Compounds 1-4 were evaluated for their inhibitory activities against 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Taxonomic review of the postica-group of Fannia Robineau-Desvoidy (Diptera, Fanniidae) from China, with the description of one new species

The Chinese fauna of the Fannia postica-group Chillcott (1961) is reviewed, the diagnostic features of this group are redefined, one new species, Fannia nudifemoratasp. n., is described, and a key to the males of nine known species is given. One new junior synonym, Fannia tigripeda Xue, Wang&Li, syn. n. for Fannia stigi Rognes is established. To facilitate comparisons of the species, Fannia aet...

متن کامل

PDFlib PLOP: PDF Linearization, Optimization, Protection

Perceptions of safety and/or cultural mores prompt individuals to seek herbal slimming aids in preference to conventional dietary, physical activity and medication-based protocols. In recent years, terpenoid-containing dietary supplements have been implicated in causing severe and sometimes fatal hepatotoxicity. Teucrium polium (germander) was the first of these herbal products to be clearly li...

متن کامل

Procerenone: a Fatty acid Triterpenoid from the Fruit Pericarp of Omphalocarpum procerum (Sapotaceae)

Phytochemical investigation of a dichloromethane-methanol (1:1) extract of the fruit pericarp of Omphalocarpum procerum which exhibited antiplasmodial activity during preliminary screening led to the isolation of the new fatty ester triterpenoid 3β-hexadecanoyloxy-28-hydroxyolean-12-en-11-one (1), together with five known compounds 2-6. The structure of the new compound as well as those of the ...

متن کامل

Procerenone: a Fatty acid Triterpenoid from the Fruit Pericarp of Omphalocarpum procerum (Sapotaceae)

Phytochemical investigation of a dichloromethane-methanol (1:1) extract of the fruit pericarp of Omphalocarpum procerum which exhibited antiplasmodial activity during preliminary screening led to the isolation of the new fatty ester triterpenoid 3β-hexadecanoyloxy-28-hydroxyolean-12-en-11-one (1), together with five known compounds 2-6. The structure of the new compound as well as those of the ...

متن کامل

A new species of Aphis Linnaeus (Hemiptera, Aphididae) living on Teucrium polium L. (Lamiaceae).

Aphis polii sp. n. living on Teucrium polium L. (Lamiaceae) is described, based on apterous and alate viviparous females and oviparous females. It has been collected from seventeen localities in mainland France, Corsica, Italy, Ukraine, Lebanon and Iran. The new species is similar to two other Aphis species that feed specifically on plants of the genus Teucrium, but has a relatively longer ulti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Molecules

دوره 18 1  شماره 

صفحات  -

تاریخ انتشار 2013